Cargando…

Cs(2)CO(3)-promoted defluorination and functionalization of α-CF(3) carbonyl compounds in the presence of N-, O-, and/or S-nucleophiles

A simple, efficient, and mild method for defluorination and functionalization of 3,3,3-trifluoro carbonyl compounds has been developed. In the present method, Cs(2)CO(3) can easily convert α-trifluoromethyl esters, amides, and ketones into β,β-S-, O- and/or N-substituted α,β-unsaturated carbonyl com...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wu, Yue, Zhang, Bingbing, Zheng, Yinying, Wang, Yuheng, Lei, Xinsheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Royal Society of Chemistry 2018
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9080061/ https://www.ncbi.nlm.nih.gov/pubmed/35542242 http://dx.doi.org/10.1039/c8ra02353k

Ejemplares similares

Direct electrochemical defluorinative carboxylation of α-CF(3) alkenes with carbon dioxide
por: Gao, Xiao-Tong, et al.
Publicado: (2020)

Microwell Fluoride Screen for Chemical, Enzymatic, and Cellular Reactions Reveals Latent Microbial Defluorination Capacity for −CF(3) Groups
por: Bygd, Madison D., et al.
Publicado: (2022)

Synthesis of α-CF(3) Amides via Palladium-Catalyzed Carbonylation of 2-Bromo-3,3,3-trifluoropropene
por: Wen, Xiao Rui, et al.
Publicado: (2023)

Defluorination and adsorption of tetrafluoroethylene (TFE) on TiO(2)(110) and Cr(2)O(3)(0001)
por: Gueriba, Jessiel Siaron, et al.
Publicado: (2021)

Complete Defluorination of Perfluorinated Compounds by Hydrated Electrons Generated from 3-Indole-acetic-acid in Organomodified Montmorillonite
por: Tian, Haoting, et al.
Publicado: (2016)

Defluorination of Polytetrafluoroethylene Surface by Hydrogen Plasma
por: Vesel, Alenka, et al.
Publicado: (2020)

Defluorination of Aqueous Perfluorooctanesulfonate by Activated Persulfate Oxidation
por: Yang, Shewei, et al.
Publicado: (2013)

Copper-catalyzed defluorinative arylboration of vinylarenes with polyfluoroarenes
por: Wu, Fu-Peng, et al.
Publicado: (2023)

α-C(sp(3))-H Arylation of Cyclic Carbonyl Compounds
por: Wang, Mei, et al.
Publicado: (2021)

Theoretical insight into OH- and Cl-initiated oxidation of CF(3)OCH(CF(3))(2) and CF(3)OCF(2)CF(2)H & fate of CF(3)OC(X•)(CF(3))(2) and CF(3)OCF(2)CF(2)X• radicals (X=O, O(2))
por: Bai, Feng-Yang, et al.
Publicado: (2017)

Controlled chemoselective defluorination and non-defluorination for [5 + 1] aromatic annulation via Meisenheimer-type nitrogen anion and radical intermediates
por: Qian, Jinlong, et al.
Publicado: (2019)

K(2)S(2)O(8)-promoted C–Se bond formation to construct α-phenylseleno carbonyl compounds and α,β-unsaturated carbonyl compounds
por: Yang, Xue-Yan, et al.
Publicado: (2020)

Direct nucleophilic trifluoromethylation of carbonyl compounds by potent greenhouse gas, fluoroform: Improving the reactivity of anionoid trifluoromethyl species in glymes
por: Saito, Takuya, et al.
Publicado: (2018)

Catalytic asymmetric defluorinative allylation of silyl enol ethers
por: Duran, Jordi, et al.
Publicado: (2023)

Mechanochemical Defluorinative Arylation of Trifluoroacetamides: An Entry to Aromatic Amides
por: Mkrtchyan, Satenik, et al.
Publicado: (2023)

General, Practical and Selective Oxidation Protocol for CF(3)S into CF(3)S(O) Group
por: Sokolenko, Liubov V., et al.
Publicado: (2019)

Unexpected Vulnerability of DPEphos to C−O Activation in the Presence of Nucleophilic Metal Hydrides
por: Cybulski, Mateusz K., et al.
Publicado: (2020)

Defluorination of Sodium Fluoroacetate by Bacteria from Soil and Plants in Brazil
por: Camboim, Expedito K. A., et al.
Publicado: (2012)

Catalytic defluorinative ketyl–olefin coupling by halogen-atom transfer
por: Bellotti, Peter, et al.
Publicado: (2022)

Morpholine-mediated defluorinative cycloaddition of gem-difluoroalkenes and organic azides
por: Huang, Tzu-Yu, et al.
Publicado: (2023)

Room Temperature Defluorination of Poly(tetrafluoroethylene) by a Magnesium Reagent
por: Sheldon, Daniel J., et al.
Publicado: (2023)

Nucleophilic Substitution Reactions in the [B(3)H(8)](−) Anion in the Presence of Lewis Acids
por: Shulyak, Alexandra T., et al.
Publicado: (2022)

Photoinduced Trifluoromethylation with CF(3)Br as a Trifluoromethyl Source: Synthesis of α-CF(3)-Substituted Ketones
por: Ma, Ransong, et al.
Publicado: (2022)

Organocatalyzed Asymmetric α-Oxidation, α-Aminoxylation and α-Amination of Carbonyl Compounds
por: Vilaivan, Tirayut, et al.
Publicado: (2010)

Developing organoboranes as phase transfer catalysts for nucleophilic fluorination using CsF
por: Kirschner, Sven, et al.
Publicado: (2022)

Degradation and Defluorination of Per- and Polyfluoroalkyl Substances by Direct Photolysis at 222 nm
por: Xin, Xiaoyue, et al.
Publicado: (2023)

Visible Light-Promoted β-Functionalization of Carbonyl Compounds in the Presence of Organic Dyes
por: Dolcini, Luigi, et al.
Publicado: (2023)

Unexpected Mechanism of Biodegradation and Defluorination of 2,2-Difluoro-1,3-Benzodioxole by Pseudomonas putida F1
por: Bygd, Madison D., et al.
Publicado: (2021)

Enantioselective nucleophilic difluoromethylation of aromatic aldehydes with Me(3)SiCF(2)SO(2)Ph and PhSO(2)CF(2)H reagents catalyzed by chiral quaternary ammonium salts
por: Ni, Chuanfa, et al.
Publicado: (2008)

Autocatalytic Carbonyl Arylation through In Situ Release of Aryl Nucleophiles from N‐Aryl‐N′‐Silyldiazenes
por: Chauvier, Clément, et al.
Publicado: (2020)

α‐Thianthrenium Carbonyl Species: The Equivalent of an α‐Carbonyl Carbocation
por: Jia, Hao, et al.
Publicado: (2022)

Biodegradation of Amphipathic Fluorinated Peptides Reveals a New Bacterial Defluorinating Activity and a New Source of Natural Organofluorine Compounds
por: Khan, Mohd Faheem, et al.
Publicado: (2023)

Substitution of fluorine in M[C(6)F(5)BF(3)] with organolithium compounds: distinctions between O- and N-nucleophiles
por: Shabalin, Anton Yu, et al.
Publicado: (2017)

Ligand-controlled regioselective and chemodivergent defluorinative functionalization of gem-difluorocyclopropanes with simple ketones
por: Lv, Leiyang, et al.
Publicado: (2021)

Trifluoromethyl Thianthrenium Triflate: A Readily Available Trifluoromethylating Reagent with Formal CF(3)(+), CF(3)(•), and CF(3)(–) Reactivity
por: Jia, Hao, et al.
Publicado: (2021)

Cesium Carbonate-Catalyzed α-Phenylchalcogenation of Carbonyl Compounds with Diphenyl Dichalcogenide
por: Nishiyama, Yutaka, et al.
Publicado: (2009)

(CF(3)CO)(2)O/CF(3)SO(3)H-mediated synthesis of 1,3-diketones from carboxylic acids and aromatic ketones
por: Kim, JungKeun, et al.
Publicado: (2014)

Diastereoselective synthesis of CF(3)-dihydrobenzofurans by [4+1] annulation of in situ-generated CF(3)-o-quinone methides and sulfur ylides
por: Jha, Babli K., et al.
Publicado: (2020)

How Do Aromatic Nitro Compounds React with Nucleophiles? Theoretical Description Using Aromaticity, Nucleophilicity and Electrophilicity Indices
por: Błaziak, Kacper, et al.
Publicado: (2020)

Synthesis of Fluorinated Amide Derivatives via a Radical N-Perfluoroalkylation–Defluorination Pathway
por: Zheng, Zhiyao, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_3lfvqe8r9rtk3bc4bgkparou8i