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The antimicrobial peptide KR-12 promotes the osteogenic differentiation of human bone marrow stem cells by stimulating BMP/SMAD signaling

KR-12 is the smallest fragment of human antimicrobial peptide cathelicidin (LL-37), and could play key roles in the treatment of multiple infections, including osteomyelitis. Our preliminary work found that KR-12 enhances the osteogenic differentiation of human bone marrow mesenchymal stem cells (HB...

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Detalles Bibliográficos
Autores principales: Li, Hui, Zhang, Shutao, Nie, Bin'en, Du, Zhe, Long, Teng, Yue, Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9080063/
https://www.ncbi.nlm.nih.gov/pubmed/35539499
http://dx.doi.org/10.1039/c8ra00750k