Diastereoselective construction of 4-indole substituted chromans bearing a ketal motif through a three-component Friedel–Crafts alkylation/ketalization sequence

The first TfOH-catalyzed three-component Friedel–Crafts alkylation/ketalization sequence of indoles, alcohols and ortho-hydroxychalcones was developed to afford a wide range of 4-indole substituted chromans bearing a ketal motif in 77–99% yields. Notably, only a simple filtration was needed to purif...

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Detalles Bibliográficos
Autores principales: Guo, Jiao-Mei, Wang, Wen-Bo, Guo, Jia, Zhu, Yan-Shuo, Bai, Xu-Guan, Jin, Shao-Jing, Wang, Qi-Lin, Bu, Zhan-Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2018
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9080074/
https://www.ncbi.nlm.nih.gov/pubmed/35539466
http://dx.doi.org/10.1039/c8ra02481b

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9080074/
https://www.ncbi.nlm.nih.gov/pubmed/35539466
http://dx.doi.org/10.1039/c8ra02481b

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