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A sensitive probe for amyloid fibril detection with strong fluorescence and early response

We synthesized a new probe, 4-[2-(2-naphthyl)-(E)-ethenyl]-benzyl(triphenyl)phosphonium bromide (NEB), to detect the formation of amyloid fibrils of bovine insulin. The fluorescence intensity of NEB in the presence of insulin fibrils was 30 times higher than that before fibrillation, with the fluore...

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Detalles Bibliográficos
Autores principales: Zheng, Xiaolin, Xu, Zhenzhen, Li, Haiyang, Fu, Hongbing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9080103/
https://www.ncbi.nlm.nih.gov/pubmed/35542196
http://dx.doi.org/10.1039/c8ra00751a