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Frontal lobe microglia, neurodegenerative protein accumulation, and cognitive function in people with HIV

Microglia are implicated in Alzheimer’s Disease (AD) pathogenesis. In a middle-aged cohort enriched for neuroinflammation, we asked whether microgliosis was related to neocortical amyloid beta (A[Formula: see text] ) deposition and neuronal phosphorylated tau (p-tau), and whether microgliosis predic...

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Detalles Bibliográficos
Autores principales: Murray, Jacinta, Meloni, Gregory, Cortes, Etty P., KimSilva, Ariadna, Jacobs, Michelle, Ramkissoon, Alyssa, Crary, John F., Morgello, Susan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9080134/
https://www.ncbi.nlm.nih.gov/pubmed/35526056
http://dx.doi.org/10.1186/s40478-022-01375-y