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Frontal lobe microglia, neurodegenerative protein accumulation, and cognitive function in people with HIV
Microglia are implicated in Alzheimer’s Disease (AD) pathogenesis. In a middle-aged cohort enriched for neuroinflammation, we asked whether microgliosis was related to neocortical amyloid beta (A[Formula: see text] ) deposition and neuronal phosphorylated tau (p-tau), and whether microgliosis predic...
Autores principales: | Murray, Jacinta, Meloni, Gregory, Cortes, Etty P., KimSilva, Ariadna, Jacobs, Michelle, Ramkissoon, Alyssa, Crary, John F., Morgello, Susan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9080134/ https://www.ncbi.nlm.nih.gov/pubmed/35526056 http://dx.doi.org/10.1186/s40478-022-01375-y |
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