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Sestrin2 in cancer: a foe or a friend?
Sestrin2 is a conserved antioxidant, metabolism regulator, and downstream of P53. Sestrin2 can suppress oxidative stress and inflammation, thereby preventing the development and progression of cancer. However, Sestrin2 attenuates severe oxidative stress by activating nuclear factor erythroid 2-relat...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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BioMed Central
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9080202/ https://www.ncbi.nlm.nih.gov/pubmed/35527284 http://dx.doi.org/10.1186/s40364-022-00380-6 |