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Synthesis of novel (benzimidazolyl)isoquinolinols and evaluation as adenosine A1 receptor tools

G protein-coupled receptors (GPCRs) constitute the largest family of transmembrane receptors in eukaryotes. The adenosine A(1) receptor (A(1)AR) is a class A GPCR that is of interest as a therapeutic target particularly in the treatment of cardiovascular disease and neuropathic pain. Increased knowl...

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Detalles Bibliográficos
Autores principales: Singh, Sameek, Cooper, Samantha L., Glenn, Jacqueline R., Beresford, Jessica, Percival, Lydia R., Tyndall, Joel D. A., Hill, Stephen J., Kilpatrick, Laura E., Vernall, Andrea J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9080270/
https://www.ncbi.nlm.nih.gov/pubmed/35542203
http://dx.doi.org/10.1039/c7ra13148h