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Synthesis of novel (benzimidazolyl)isoquinolinols and evaluation as adenosine A1 receptor tools
G protein-coupled receptors (GPCRs) constitute the largest family of transmembrane receptors in eukaryotes. The adenosine A(1) receptor (A(1)AR) is a class A GPCR that is of interest as a therapeutic target particularly in the treatment of cardiovascular disease and neuropathic pain. Increased knowl...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9080270/ https://www.ncbi.nlm.nih.gov/pubmed/35542203 http://dx.doi.org/10.1039/c7ra13148h |