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Copper complexes as prospective anticancer agents: in vitro and in vivo evaluation, selective targeting of cancer cells by DNA damage and S phase arrest

A series of six new bis(thiosemicarbazone)copper(i) complexes of the type [Cu(L(1–6))(2)Cl] (1–6) have been synthesized and characterized. The molecular structure of the ligand L(4) was determined by the single crystal XRD method. All the complexes adopted trigonal planar (Y-shaped) geometry. All th...

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Detalles Bibliográficos
Autores principales: Mahendiran, Dharmasivam, Amuthakala, Sethu, Bhuvanesh, Nattamai S. P., Kumar, Raju Senthil, Rahiman, Aziz Kalilur
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9080330/
https://www.ncbi.nlm.nih.gov/pubmed/35540520
http://dx.doi.org/10.1039/c8ra00954f