Diagnostic Accuracy of Immunohistochemistry in Detecting MGMT Methylation Status in Patients with Glioma

BACKGROUND: The O6-methylguanine-DNA methyltransferase (MGMT) gene prevents mismatch in DNA replication and transcription by repairing mutagenic DNA lesions. MGMT is a predictor biomarker of chemotherapy in high-grade and low-grade gliomas based on high-risk clinical conditions. It also can be used...

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Detalles Bibliográficos
Autores principales: Sahara, Nita, Hartanto, Rachmat Andi, Yoshuantari, Naomi, Dananjoyo, Kusumo, Widodo, Irianiwati, Malueka, Rusdy Ghazali, Dwianingsih, Ery Kus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: West Asia Organization for Cancer Prevention 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9080354/
https://www.ncbi.nlm.nih.gov/pubmed/34967558
http://dx.doi.org/10.31557/APJCP.2021.22.12.3803

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9080354/
https://www.ncbi.nlm.nih.gov/pubmed/34967558
http://dx.doi.org/10.31557/APJCP.2021.22.12.3803

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