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Diagnostic Accuracy of Immunohistochemistry in Detecting MGMT Methylation Status in Patients with Glioma

BACKGROUND: The O6-methylguanine-DNA methyltransferase (MGMT) gene prevents mismatch in DNA replication and transcription by repairing mutagenic DNA lesions. MGMT is a predictor biomarker of chemotherapy in high-grade and low-grade gliomas based on high-risk clinical conditions. It also can be used...

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Detalles Bibliográficos
Autores principales:	Sahara, Nita, Hartanto, Rachmat Andi, Yoshuantari, Naomi, Dananjoyo, Kusumo, Widodo, Irianiwati, Malueka, Rusdy Ghazali, Dwianingsih, Ery Kus
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	West Asia Organization for Cancer Prevention 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9080354/ https://www.ncbi.nlm.nih.gov/pubmed/34967558 http://dx.doi.org/10.31557/APJCP.2021.22.12.3803

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