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Design, synthesis, and biological evaluation of AV6 derivatives as novel dual reactivators of latent HIV-1
The “shock and kill” strategy might be a promising therapeutic approach for HIV/AIDS due to the existence of latent viral reservoirs. A major challenge of the “shock and kill” strategy arises from the general lack of clinically effective latency-reversing agents (LRAs). The 2-methylquinoline derivat...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9080425/ https://www.ncbi.nlm.nih.gov/pubmed/35539279 http://dx.doi.org/10.1039/c8ra01216d |