Humanization and directed evolution of the selenium-containing scFv phage abzyme

According to the binding site structure and the catalytic mechanism of the native glutathione peroxidase (GPX), three glutathione derivatives, GSH-S-DNP butyl ester (hapten Be), GSH-S-DNP hexyl ester (hapten He) and GSH-S-DNP hexamethylene ester (hapten Hme) were synthesized. By a four-round panning...

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Detalles Bibliográficos
Autores principales: Xu, Yan, Li, Pengju, Nie, Jiaojiao, Zhao, Qi, Guan, Shanshan, Kuai, Ziyu, Qiao, Yongbo, Jiang, Xiaoyu, Li, Ying, Li, Wei, Shi, Yuhua, Kong, Wei, Shan, Yaming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2018
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9080455/
https://www.ncbi.nlm.nih.gov/pubmed/35539266
http://dx.doi.org/10.1039/c8ra02798f

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9080455/
https://www.ncbi.nlm.nih.gov/pubmed/35539266
http://dx.doi.org/10.1039/c8ra02798f

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