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Immediate separation of microneedle tips from base array during skin insertion for instantaneous drug delivery

We have developed an insertion-responsive microneedle (IRMN) system that enables prompt drug delivery through the skin without attaching a skin patch. This system consists of square pyramidal hyaluronic acid (HA) microneedle tips and polycaprolactone (PCL) base arrays. During skin insertion, HA tips...

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Detalles Bibliográficos
Autores principales: Jun, Hyesun, Ahn, Myun-Hwan, Choi, In-Jeong, Baek, Seung-Ki, Park, Jung-Hwan, Choi, Seong-O
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9080469/
https://www.ncbi.nlm.nih.gov/pubmed/35542069
http://dx.doi.org/10.1039/c8ra02334d