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Co-delivery of doxorubicin and shRNA of Beclin1 by folate receptor targeted pullulan-based multifunctional nanomicelles for combinational cancer therapy

Doxorubicin (DOX) is a widely-used effective antitumor agent. However, its clinical application is limited due to its side effects including anti-apoptotic defense of cancer cells caused by DOX-induced autophagy and deleterious effects in normal tissues. Therefore, in this study, a new folate (FA)-d...

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Detalles Bibliográficos
Autores principales: Chen, Lili, Qian, Ming, Zhang, Liuwei, Xia, Jing, Bao, Yongming, Wang, Jingyun, Guo, Lianying, Li, Yachen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9080481/
https://www.ncbi.nlm.nih.gov/pubmed/35542072
http://dx.doi.org/10.1039/c8ra01679h