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Co-delivery of doxorubicin and shRNA of Beclin1 by folate receptor targeted pullulan-based multifunctional nanomicelles for combinational cancer therapy
Doxorubicin (DOX) is a widely-used effective antitumor agent. However, its clinical application is limited due to its side effects including anti-apoptotic defense of cancer cells caused by DOX-induced autophagy and deleterious effects in normal tissues. Therefore, in this study, a new folate (FA)-d...
Autores principales: | Chen, Lili, Qian, Ming, Zhang, Liuwei, Xia, Jing, Bao, Yongming, Wang, Jingyun, Guo, Lianying, Li, Yachen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9080481/ https://www.ncbi.nlm.nih.gov/pubmed/35542072 http://dx.doi.org/10.1039/c8ra01679h |
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