Cargando…

Cyclization of secondarily structured oligonucleotides to single-stranded rings by using Taq DNA ligase at high temperatures

Single-stranded DNA rings play important roles in nanoarchitectures, molecular machines, DNA detection, etc. Although T4 DNA ligase has been widely employed to cyclize single-stranded oligonucleotides into rings, the cyclization efficiency is very low when the oligonucleotides (l-DNAs) take complica...

Descripción completa

Detalles Bibliográficos
Autores principales: Cui, Yixiao, Han, Xutiange, An, Ran, Zhou, Guangqing, Komiyama, Makoto, Liang, Xingguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9080623/
https://www.ncbi.nlm.nih.gov/pubmed/35539641
http://dx.doi.org/10.1039/c8ra02804d