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Cyclization of secondarily structured oligonucleotides to single-stranded rings by using Taq DNA ligase at high temperatures
Single-stranded DNA rings play important roles in nanoarchitectures, molecular machines, DNA detection, etc. Although T4 DNA ligase has been widely employed to cyclize single-stranded oligonucleotides into rings, the cyclization efficiency is very low when the oligonucleotides (l-DNAs) take complica...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9080623/ https://www.ncbi.nlm.nih.gov/pubmed/35539641 http://dx.doi.org/10.1039/c8ra02804d |