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A sensitive approach for simultaneous quantification of carbonyl and hydroxyl steroids using 96-well SPE plates based on stable isotope coded-derivatization-UPLC-MRM: method development and application

Steroid hormones are crucial substances that mediate a wide range of vital physiological functions. Because of the important biological significance of steroids, this paper presents a new targeted metabolic method based on adding stable isotope tags to hydroxyl containing and carbonyl containing ste...

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Detalles Bibliográficos
Autores principales: Liu, Chuanxin, Sheng, Xue, Wang, Yuming, Yin, Jia, Huang, Wei, Fan, Yunshuang, Li, Yubo, Zhang, Yanjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9080693/
https://www.ncbi.nlm.nih.gov/pubmed/35540992
http://dx.doi.org/10.1039/c8ra01372a