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A study on a telo21 G-quadruplex DNA specific binding ligand: enhancing the molecular recognition ability via the amino group interactions

A symmetric ligand is synthesized composed of a core N-methylpyridinium scaffold and two para-substituted benzyl groups through a flexible ethylene bridge to form a novel three-ring-conjugated system. The ligand system was found to have only weak background fluorescent signal in aqueous or physiolog...

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Detalles Bibliográficos
Autores principales: Li, Dongli, Hou, Jin-Qiang, Long, Wei, Lu, Yu-Jing, Wong, Wing-Leung, Zhang, Kun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9080739/
https://www.ncbi.nlm.nih.gov/pubmed/35541662
http://dx.doi.org/10.1039/c8ra03833c