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Construction of PLGA/JNK3-shRNA nanoparticles and their protective role in hippocampal neuron apoptosis induced by oxygen and glucose deprivation

C-Jun N-terminal kinase 3 (JNK3) activation plays an essential role in the pathophysiology of cerebral ischemia. However, to date, no specific interventions with good efficacy have been reported. Therefore, in this study, we constructed a PLGA/JNK3-shRNA nanoparticle and examined its effects on neur...

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Detalles Bibliográficos
Autores principales: Zheng, Jin, Qi, Jianguo, Zou, Quan, Zhang, Zhenzhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9080791/
https://www.ncbi.nlm.nih.gov/pubmed/35541669
http://dx.doi.org/10.1039/c8ra00679b