Engineering substrate promiscuity in 2,4-dichlorophenol hydroxylase by in silico design

2,4-Dichlorophenol hydroxylase (2,4-DCP hydroxylase) is a key enzyme in the degradation of 2,4-dichlorophenoxyacetic acid in the hydroxylation step in many bacteria. Our previous study demonstrated that a 2,4-DCP hydroxylase (TfdB-JLU) exhibits broad substrate specificity for chlorophenols (CPs) and...

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Detalles Bibliográficos
Autores principales: Wang, Ye, Zhang, Chengkai, An, Song, Fang, Xuexun, Yu, Dahai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2018
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9080915/
https://www.ncbi.nlm.nih.gov/pubmed/35539933
http://dx.doi.org/10.1039/c8ra03229g

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9080915/
https://www.ncbi.nlm.nih.gov/pubmed/35539933
http://dx.doi.org/10.1039/c8ra03229g

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