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Microbial transformation of mestanolone by Macrophomina phaseolina and Cunninghamella blakesleeana and anticancer activities of the transformed products

The microbial transformation of anabolic androgenic steroid mestanolone (1) with Macrophomina phaseolina and Cunninghamella blakesleeana has afforded seven metabolites. The structures of these metabolites were characterized as 17β-hydroxy-17α-methyl-5α-androsta-1-ene-3,11-dione (2), 14α,17β-dihydrox...

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Detalles Bibliográficos
Autores principales: Farooq, Rabia, Hussain, Nusrat, Yousuf, Sammer, Atia-tul-Wahab, Ahmad, Malik Shoaib, Atta-ur-Rahman, Choudhary, M. Iqbal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9081080/
https://www.ncbi.nlm.nih.gov/pubmed/35541749
http://dx.doi.org/10.1039/c8ra01309h