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Microbial transformation of mestanolone by Macrophomina phaseolina and Cunninghamella blakesleeana and anticancer activities of the transformed products
The microbial transformation of anabolic androgenic steroid mestanolone (1) with Macrophomina phaseolina and Cunninghamella blakesleeana has afforded seven metabolites. The structures of these metabolites were characterized as 17β-hydroxy-17α-methyl-5α-androsta-1-ene-3,11-dione (2), 14α,17β-dihydrox...
Autores principales: | Farooq, Rabia, Hussain, Nusrat, Yousuf, Sammer, Atia-tul-Wahab, Ahmad, Malik Shoaib, Atta-ur-Rahman, Choudhary, M. Iqbal |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9081080/ https://www.ncbi.nlm.nih.gov/pubmed/35541749 http://dx.doi.org/10.1039/c8ra01309h |
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