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Cerebrospinal fluid regulates skull bone marrow niches via direct access through dural channels

It remains unclear how immune cells from skull bone marrow niches are recruited to the meninges. Here, we report that cerebrospinal fluid (CSF) accesses skull bone marrow via dura-skull channels, and CSF proteins signal onto diverse cell types within the niches. Following spinal cord injury, CSF-bor...

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Detalles Bibliográficos
Autores principales: Mazzitelli, Jose A., Smyth, Leon C.D., Cross, Kevin A., Dykstra, Taitea, Sun, Jerry, Du, Siling, Mamuladze, Tornike, Smirnov, Igor, Rustenhoven, Justin, Kipnis, Jonathan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9081158/
https://www.ncbi.nlm.nih.gov/pubmed/35301477
http://dx.doi.org/10.1038/s41593-022-01029-1