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Synthesis of 3-(5-amino-1H-1,2,4-triazol-3-yl)propanamides and their tautomerism

Two complementary pathways for the preparation of N-substituted 3-(5-amino-1H-1,2,4-triazol-3-yl)propanamides (5) were proposed and successfully realized in the synthesis of 20 representative examples. These methods use the same types of starting materials viz. succinic anhydride, aminoguanidine hyd...

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Detalles Bibliográficos
Autores principales: Lim, Felicia Phei Lin, Tan, Lin Yuing, Tiekink, Edward R. T., Dolzhenko, Anton V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9081160/
https://www.ncbi.nlm.nih.gov/pubmed/35539716
http://dx.doi.org/10.1039/c8ra04576c