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Pharmacokinetics, Mass Balance, Excretion, and Tissue Distribution of Plasmalogen Precursor PPI-1011

PPI-1011 is a synthetic plasmalogen precursor in development as a treatment for multiple plasmalogen-deficiency disorders. Previous work has demonstrated the ability of PPI-1011 to augment plasmalogens and its effects in vitro and in vivo, however, the precise uptake and distribution across tissues...

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Detalles Bibliográficos
Autores principales: Smith, Tara, Knudsen, Kaeli J., Ritchie, Shawn A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9081329/
https://www.ncbi.nlm.nih.gov/pubmed/35547803
http://dx.doi.org/10.3389/fcell.2022.867138