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FUCCI-Based Live Imaging Platform Reveals Cell Cycle Dynamics and Identifies Pro-proliferative Compounds in Human iPSC-Derived Cardiomyocytes

One of the major goals in cardiac regeneration research is to replace lost ventricular tissue with new cardiomyocytes. However, cardiomyocyte proliferation drops to low levels in neonatal hearts and is no longer efficient in compensating for the loss of functional myocardium in heart disease. We gen...

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Detalles Bibliográficos
Autores principales: Murganti, Francesca, Derks, Wouter, Baniol, Marion, Simonova, Irina, Trus, Palina, Neumann, Katrin, Khattak, Shahryar, Guan, Kaomei, Bergmann, Olaf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9081338/
https://www.ncbi.nlm.nih.gov/pubmed/35548410
http://dx.doi.org/10.3389/fcvm.2022.840147