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Tandem four-component reaction for efficient synthesis of dihydrothiophene with substituted amino acid ethyl esters

The one-pot four-component reaction of aromatic aldehydes, malononitrile, 1,3-thiazolidinedione and ethyl glycinate hydrochloride in ethanol in the presence of triethylamine afforded trans-dihydrothiophene ureidoformamide derivatives in moderate to good yields. The other α-amino acid ethyl esters re...

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Detalles Bibliográficos
Autores principales:	Sun, Jing, Zhang, Yu, Yan, Chao-Guo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Royal Society of Chemistry 2018
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9081350/ https://www.ncbi.nlm.nih.gov/pubmed/35539758 http://dx.doi.org/10.1039/c8ra03605e

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