Phenethylisothiocyanate Potentiates Platinum Therapy by Reversing Cisplatin Resistance in Cervical Cancer

Acquired cisplatin resistance in cervical cancer therapy is principally caused by reduction in intracellular drug accumulation, which is exerted by hyperactivation of the oncogenic PI3K/Akt signaling axis and overexpression of cisplatin-exporter MRP2 along with prosurvival effectors NF-κB and IAPs i...

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Detalles Bibliográficos
Autores principales: Mahapatra, Elizabeth, Sengupta, Debomita, Kumar, Ravindra, Dehury, Budheswar, Das, Salini, Roy, Madhumita, Mukherjee, Sutapa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9081374/
https://www.ncbi.nlm.nih.gov/pubmed/35548339
http://dx.doi.org/10.3389/fphar.2022.803114

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9081374/
https://www.ncbi.nlm.nih.gov/pubmed/35548339
http://dx.doi.org/10.3389/fphar.2022.803114

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