A novel square-planar Pt(ii) complex as a monomeric and dimeric G-quadruplex DNA binder

A novel phenanthroimidazole ethylenediamine Pt(ii) complex with coumarin derivative (1) was synthesized and showed higher affinity, selectivity and thermal stabilization for mixed-type dimeric G-quadruplexes (G2T1) over monomeric G-quadruplexes (G1) and duplex DNA. Complex 1 could bind to G-quadrupl...

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Detalles Bibliográficos
Autores principales: Zhou, Chun-Qiong, Li, Zi-Qi, Liao, Ting-Cong, Ma, Tian-Zhu, Chen, Shuo-Bin, Liang, Yuan-Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2018
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9081585/
https://www.ncbi.nlm.nih.gov/pubmed/35540167
http://dx.doi.org/10.1039/c8ra03606c

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9081585/
https://www.ncbi.nlm.nih.gov/pubmed/35540167
http://dx.doi.org/10.1039/c8ra03606c

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