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A novel square-planar Pt(ii) complex as a monomeric and dimeric G-quadruplex DNA binder

A novel phenanthroimidazole ethylenediamine Pt(ii) complex with coumarin derivative (1) was synthesized and showed higher affinity, selectivity and thermal stabilization for mixed-type dimeric G-quadruplexes (G2T1) over monomeric G-quadruplexes (G1) and duplex DNA. Complex 1 could bind to G-quadrupl...

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Detalles Bibliográficos
Autores principales:	Zhou, Chun-Qiong, Li, Zi-Qi, Liao, Ting-Cong, Ma, Tian-Zhu, Chen, Shuo-Bin, Liang, Yuan-Yuan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Royal Society of Chemistry 2018
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9081585/ https://www.ncbi.nlm.nih.gov/pubmed/35540167 http://dx.doi.org/10.1039/c8ra03606c

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