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Reversing Epithelial Polarity in Pluripotent Stem Cell-Derived Intestinal Organoids

The inner surface of the intestine is a dynamic system, composed of a single layer of polarized epithelial cells. The development of intestinal organoids was a major breakthrough since they robustly recapitulate intestinal architecture, regional specification and cell composition in vitro. However,...

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Detalles Bibliográficos
Autores principales: Kakni, Panagiota, López-Iglesias, Carmen, Truckenmüller, Roman, Habibović, Pamela, Giselbrecht, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9081652/
https://www.ncbi.nlm.nih.gov/pubmed/35547177
http://dx.doi.org/10.3389/fbioe.2022.879024