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Pro-Arrhythmic Effects of Discontinuous Conduction at the Purkinje Fiber-Ventricle Junction Arising From Heart Failure-Induced Ionic Remodeling – Insights From Computational Modelling

Heart failure is associated with electrical remodeling of the electrical properties and kinetics of the ion channels and transporters that are responsible for cardiac action potentials. However, it is still unclear whether heart failure-induced ionic remodeling can affect the conduction of excitatio...

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Detalles Bibliográficos
Autores principales: Jian, Kun, Li, Chen, Hancox, Jules C., Zhang, Henggui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9081695/
https://www.ncbi.nlm.nih.gov/pubmed/35547576
http://dx.doi.org/10.3389/fphys.2022.877428