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Spectroscopy, Structure, Biomacromolecular Interactions, and Antiproliferation Activity of a Fe(II) Complex With DPA-Bpy as Pentadentate Ligand

An Fe(II) complex with DPA-Bpy (DPA-Bpy = N,N-bis(2-pyridinylmethyl)-2,20-bipyridine-6 -methanamine) as the ligand was synthesized and characterized to mimic bleomycin. The binding constants (K (b)) of the complex with calf thymus DNA and human serum albumin (HSA) were quantitatively evaluated using...

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Detalles Bibliográficos
Autores principales: Bai, Hehe, Shi, Jia, Guo, Qingyu, Wang, Wenming, Zhang, Zhigang, Li, Yafeng, Vennampalli, Manohar, Zhao, Xuan, Wang, Hongfei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9081768/
https://www.ncbi.nlm.nih.gov/pubmed/35548676
http://dx.doi.org/10.3389/fchem.2022.888693