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Interaction Between CD34(+) Fibrocytes and Airway Smooth Muscle Promotes IL-8 Production and Akt/PRAS40/mTOR Signaling in Asthma

BACKGROUND: The circulating progenitor cells of fibroblasts (fibrocytes) have been shown to infiltrate the airway smooth muscle compartment of asthma patients; however, the pathological significance of this discovery has yet to be elucidated. This study established a co-culture model of airway smoot...

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Detalles Bibliográficos
Autores principales: Lin, Ting-Yu, Chang, Po-Jui, Lo, Chun-Yu, Lo, Yu-Lun, Yu, Chih-Teng, Lin, Shu-Min, Kuo, Chih-His Scott, Lin, Horng-Chyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9081978/
https://www.ncbi.nlm.nih.gov/pubmed/35547213
http://dx.doi.org/10.3389/fmed.2022.823994