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Synthesis of an unusual quinazoline alkaloid: theoretical and experimental investigations of its structural, electronic, molecular and biological properties

An unusual quinazoline alkaloid (1) was obtained when 2-aminobenzaldehyde was refluxed with pyrrolidine in ethanol for 12 h. The synthesized compound was characterized using spectral data analysis augmented with X-ray and literature precedent. Single crystal analysis depicted four conformations diff...

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Detalles Bibliográficos
Autores principales: Lone, Shabir H., Jameel, Salman, Bhat, Muzzaffar A., Lone, Rayees A., Butcher, Ray J., Bhat, Khursheed A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9082197/
https://www.ncbi.nlm.nih.gov/pubmed/35542000
http://dx.doi.org/10.1039/c8ra00138c