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Non-apoptotic activation of Drosophila caspase-2/9 modulates JNK signaling, the tumor microenvironment, and growth of wound-like tumors

Resistance to apoptosis due to caspase deregulation is considered one of the main hallmarks of cancer. However, the discovery of novel non-apoptotic caspase functions has revealed unknown intricacies about the interplay between these enzymes and tumor progression. To investigate this biological prob...

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Detalles Bibliográficos
Autores principales: Cui Xu, Derek, Wang, Li, Yamada, Kenneth M., Baena-Lopez, Luis Alberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9082238/
https://www.ncbi.nlm.nih.gov/pubmed/35443185
http://dx.doi.org/10.1016/j.celrep.2022.110718