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P-Stereodefined phosphorothioate analogs of glycol nucleic acids—synthesis and structural properties

Enantiomerically pure, protected acyclic nucleosides of the GNA type (glycol nucleic acids) ((G)N′), obtained from (R)-(+)- and (S)-(−)-glycidols and the four canonical DNA nucleobases (Ade, Cyt, Gua and Thy), were transformed into 3′-O-DMT-protected 2-thio-4,4-pentamethylene-1,3,2-oxathiaphospholan...

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Detalles Bibliográficos
Autores principales: Tomaszewska-Antczak, Agnieszka, Jastrzębska, Katarzyna, Maciaszek, Anna, Mikołajczyk, Barbara, Guga, Piotr
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9082371/
https://www.ncbi.nlm.nih.gov/pubmed/35542141
http://dx.doi.org/10.1039/c8ra05568h