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P-Stereodefined phosphorothioate analogs of glycol nucleic acids—synthesis and structural properties
Enantiomerically pure, protected acyclic nucleosides of the GNA type (glycol nucleic acids) ((G)N′), obtained from (R)-(+)- and (S)-(−)-glycidols and the four canonical DNA nucleobases (Ade, Cyt, Gua and Thy), were transformed into 3′-O-DMT-protected 2-thio-4,4-pentamethylene-1,3,2-oxathiaphospholan...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Royal Society of Chemistry
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9082371/ https://www.ncbi.nlm.nih.gov/pubmed/35542141 http://dx.doi.org/10.1039/c8ra05568h |