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Liver vitronectin release into the bloodstream increases due to reduced vagal muscarinic signaling after cerebral stroke in female mice

Vitronectin (VTN) is a glycoprotein enriched in the blood and activates integrin receptors. VTN blood levels increase only in female mice 24 h after an ischemic stroke and exacerbate brain injury through IL‐6‐driven inflammation, but the VTN induction mechanism is unknown. Here, a 30 min middle cere...

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Detalles Bibliográficos
Autores principales: Keasey, Matthew P., Lovins, Chiharu, Jia, Cuihong, Hagg, Theo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9082388/
https://www.ncbi.nlm.nih.gov/pubmed/35531929
http://dx.doi.org/10.14814/phy2.15301