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Phospho‐specific plasma p‐tau181 assay detects clinical as well as asymptomatic Alzheimer's disease

OBJECTIVE: Plasma phosphorylated‐tau‐181 (p‐tau181) reliably detects clinical Alzheimer's disease (AD) as well as asymptomatic amyloid‐β (Aβ) pathology, but is consistently quantified with assays using antibody AT270, which cross‐reacts with p‐tau175. This study investigates two novel phospho‐s...

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Detalles Bibliográficos
Autores principales: De Meyer, Steffi, Vanbrabant, Jeroen, Schaeverbeke, Jolien M., Reinartz, Mariska, Luckett, Emma S., Dupont, Patrick, Van Laere, Koen, Stoops, Erik, Vanmechelen, Eugeen, Poesen, Koen, Vandenberghe, Rik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9082389/
https://www.ncbi.nlm.nih.gov/pubmed/35502634
http://dx.doi.org/10.1002/acn3.51553