Computational investigations of the binding mechanism of novel benzophenone imine inhibitors for the treatment of breast cancer

4-Hydroxytamoxifen (4-OHT), the most common hormone used for the treatment of breast cancer, is a selective estrogen receptor modulator (SERM) inhibitor that acts as an antagonist in breast tissue and a partial agonist in the endometrium. However, the detailed molecular mechanism of 4-OHT structure...

Descripción completa

Detalles Bibliográficos
Autores principales: Shtaiwi, Amneh, Adnan, Rohana, Khairuddean, Melati, Khan, Shafi Ullah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2019
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9082406/
https://www.ncbi.nlm.nih.gov/pubmed/35541022
http://dx.doi.org/10.1039/c9ra04759j

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9082406/
https://www.ncbi.nlm.nih.gov/pubmed/35541022
http://dx.doi.org/10.1039/c9ra04759j

Ejemplares similares