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Computational investigations of the binding mechanism of novel benzophenone imine inhibitors for the treatment of breast cancer

4-Hydroxytamoxifen (4-OHT), the most common hormone used for the treatment of breast cancer, is a selective estrogen receptor modulator (SERM) inhibitor that acts as an antagonist in breast tissue and a partial agonist in the endometrium. However, the detailed molecular mechanism of 4-OHT structure...

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Detalles Bibliográficos
Autores principales:	Shtaiwi, Amneh, Adnan, Rohana, Khairuddean, Melati, Khan, Shafi Ullah
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Royal Society of Chemistry 2019
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9082406/ https://www.ncbi.nlm.nih.gov/pubmed/35541022 http://dx.doi.org/10.1039/c9ra04759j

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