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Hydrogen Peroxide Scavenging Restores N-Type Calcium Channels in Cardiac Vagal Postganglionic Neurons and Mitigates Myocardial Infarction-Evoked Ventricular Arrhythmias in Type 2 Diabetes Mellitus

OBJECTIVE: Withdrawal of cardiac vagal activity is associated with ventricular arrhythmia-related high mortality in patients with type 2 diabetes mellitus (T2DM). Our recent study found that reduced cell excitability of cardiac vagal postganglionic (CVP) neurons is involved in cardiac vagal dysfunct...

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Detalles Bibliográficos
Autores principales: Zhang, Dongze, Tu, Huiyin, Hu, Wenfeng, Duan, Bin, Zimmerman, Matthew C., Li, Yu-Long
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9082497/
https://www.ncbi.nlm.nih.gov/pubmed/35548411
http://dx.doi.org/10.3389/fcvm.2022.871852