High-glucose 3D INS-1 cell model combined with a microfluidic circular concentration gradient generator for high throughput screening of drugs against type 2 diabetes

In vitro models for screening of drugs against type 2 diabetes are crucial for the pharmaceutical industry. This paper presents a new approach for integration of a three-dimensionally-cultured insulinoma cell line (INS-1 cell) incubated in a high concentration of glucose as a new model. In this mode...

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Detalles Bibliográficos
Autores principales: Luo, Yong, Zhang, Xiuli, Li, Yujiao, Deng, Jiu, Li, Xiaorui, Qu, Yueyang, Lu, Yao, Liu, Tingjiao, Gao, Zhigang, Lin, Bingcheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2018
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9082620/
https://www.ncbi.nlm.nih.gov/pubmed/35539797
http://dx.doi.org/10.1039/c8ra04040k

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9082620/
https://www.ncbi.nlm.nih.gov/pubmed/35539797
http://dx.doi.org/10.1039/c8ra04040k

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