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V-ATPase is a universal regulator of LC3-associated phagocytosis and non-canonical autophagy

Non-canonical autophagy is a key cellular pathway in immunity, cancer, and neurodegeneration, characterized by conjugation of ATG8 to endolysosomal single membranes (CASM). CASM is activated by engulfment (endocytosis, phagocytosis), agonists (STING, TRPML1), and infection (influenza), dependent on...

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Detalles Bibliográficos
Autores principales: Hooper, Kirsty M., Jacquin, Elise, Li, Taoyingnan, Goodwin, Jonathan M., Brumell, John H., Durgan, Joanne, Florey, Oliver
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9082624/
https://www.ncbi.nlm.nih.gov/pubmed/35511089
http://dx.doi.org/10.1083/jcb.202105112