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V-ATPase is a universal regulator of LC3-associated phagocytosis and non-canonical autophagy
Non-canonical autophagy is a key cellular pathway in immunity, cancer, and neurodegeneration, characterized by conjugation of ATG8 to endolysosomal single membranes (CASM). CASM is activated by engulfment (endocytosis, phagocytosis), agonists (STING, TRPML1), and infection (influenza), dependent on...
Autores principales: | Hooper, Kirsty M., Jacquin, Elise, Li, Taoyingnan, Goodwin, Jonathan M., Brumell, John H., Durgan, Joanne, Florey, Oliver |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9082624/ https://www.ncbi.nlm.nih.gov/pubmed/35511089 http://dx.doi.org/10.1083/jcb.202105112 |
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