Comparative studies on the interaction of anticancer drug irinotecan with dsDNA and ssDNA

A systematic comparative study on the binding of anticancer drug irinotecan (Irino) with dsDNA and ssDNA was investigated in phosphate buffer solutions using voltammetric and spectroscopic methods. The voltammetric results show that the Irino molecule, acting as an intercalator, is inserted into the...

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Detalles Bibliográficos
Autores principales: Temerk, Yassien, Ibrahim, Mohamed, Ibrahim, Hossieny, Schuhmann, Wolfgang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2018
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9082630/
https://www.ncbi.nlm.nih.gov/pubmed/35539780
http://dx.doi.org/10.1039/c8ra03231a

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9082630/
https://www.ncbi.nlm.nih.gov/pubmed/35539780
http://dx.doi.org/10.1039/c8ra03231a

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