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Comparative studies on the interaction of anticancer drug irinotecan with dsDNA and ssDNA
A systematic comparative study on the binding of anticancer drug irinotecan (Irino) with dsDNA and ssDNA was investigated in phosphate buffer solutions using voltammetric and spectroscopic methods. The voltammetric results show that the Irino molecule, acting as an intercalator, is inserted into the...
Autores principales: | Temerk, Yassien, Ibrahim, Mohamed, Ibrahim, Hossieny, Schuhmann, Wolfgang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9082630/ https://www.ncbi.nlm.nih.gov/pubmed/35539780 http://dx.doi.org/10.1039/c8ra03231a |
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